Oculogyric crisis is an acute dystonia of the ocular muscles, usually causing upward and lateral displacement of the eye. It is often accompanied by a disorder of attention (obsessive, persistent thoughts), with or without dystonic or dyskinetic movements. It occurs particularly
with symptomatic (secondary), as opposed to idiopathic (primary), dystonias, for example post-encephalitic and neuroleptic-induced dystonia, the latter now being the most common cause. This is usually an acute effect but may on occasion be seen as a consequence of chronic therapy (tardive oculogyric crisis).
Treatment of acute neuroleptic-induced dystonia is either parenteral benzodiazepine or an anticholinergic agent, such as procyclidine, benztropine, or trihexyphenidyl.
Leigh RJ, Foley JM, Remler BF, Civil RH. Oculogyric crisis: a syndrome of thought disorder and ocular deviation. Annals of Neurology1987; 22: 13-17